David S Zingmond, MD - UCLA Health Westwood Internal Medicine 200

Medical Director, Extensivist Program and Care Transitions, Department of MedicinePatient StoriesTeam-based care has kept one patient healthy

Dr. Szilagyi is a pediatric health services and clinical researcher with an overall mission to improve access to healthcare, quality of care, and health outcomes for children. He has focused his research on improving the delivery of healthcare in primary care and other settings in three related areas: immunization delivery, healthcare financing, and improved care for children with chronic diseases. His immunization delivery studies have led to national recommendations for vaccine financing, evidence-based strategies in primary care to raise immunization rates, a renewed focus on HPV vaccinations and influenza vaccinations, and use of technology to improve immunization delivery. His studies on healthcare financing for children contributed heavily to the passage of the State Children’s Health Insurance Program (SCHIP, now known as CHIP) in 1998, the SCHIP reauthorization debate in 2008, the Children's Health Insurance Program Reauthorization Act of 2009 (CHIPRA), and the recent reauthorization of CHIP in 2015. In collaboration with many others, his studies on common chronic diseases of childhood and adolescence have contributed to improved management, care coordination, and building of medical homes to improve the care of children with chronic conditions such as asthma, mental health, behavioral, and developmental conditions, and childhood obesity. His work has extended far beyond academics - he has advised CDC on immunization strategies, advised federal and state policy-makers on health insurance for children, and has been appointed to the Medicaid and CHIP Payment and Access Commission (MACPAC), a prestigious organization that advised Congress and the Secretary of Health and Human Services about Medicaid and CHIP. He is also a national leader in pediatric education, particularly in training academic general pediatric fellows and in building the field of health services researchers. In 2016 he was appointed to the Advisory Committee on Immunization Practices (ACIP) which makes recommendations about vaccinations for the nation's child, adolescent and adult population. Contact Information: PSzilagyi@mednet.ucla.edu

Dr. Andreas Schwingshackl's MD and PhD training provides the ideal framework for his work as a clinician-scientist in the field of lung inflammation, injury and repair. Dr. Schwingshackl's current research focuses on the role of stretch-activated potassium channels in the development of ventilator-induced lung injury, including inflammatory mediator secretion, loss of epithelial barrier function and lung repair mechanisms. In 2009 he discovered the expression of stretch-activated, 2-pore domain potassium (K2P) channels in the lung epithelium and in the following years he demonstrated that the TREK subfamily of K2P channels plays a crucial role in the development of hyperoxia- and mechanical stretch-induced lung injury. To study these TREK channels, Dr. Schwingshackl's lab created several stable, TREK-1 deficient and TREK-1 overexpressing murine and human lung epithelial cells lines and they currently employ TREK-deficient mouse models, in conjunction with state-of the-art molecular, genetic, electrophysiological and imaging techniques, such as confocal immunofluorescence microscopy, electron microscopy and atomic force microscopy (AFM). His work in this field has been recognized and supported by national and international funding agencies such as the Alberta Heritage Foundation for Medical Research, the Austrian Hans and Blanca Moser Foundation, the University of Tennessee Children's Foundation Research Institute, the American Lung Association and the National Institutes for Health (K12, K08, and R01 awards). Currently, Dr. Schwingshackl contributes to the field of pulmonary medicine by serving as Associate Editor for Frontiers in Pediatric Critical Care, as a standing member of the American Thoracic Society (ATS) Program Committee for Respiratory, Cell and Molecular Cell Biology and the American Heart Association (AHA) grant review panel (BSc Lung), and as an ad-hoc reviewer for more than 10 scientific journals. Recently, the University of California Los Angeles (UCLA) has rewarded his research efforts in pulmonary medicine with the prestigious Dorothy & Robert Keyser Endowed Chair in Pediatrics.