O'Brien, Patricia O MD

Dr. Ayala is the director of the Hemophilia and Bleeding Disorders Treatment Center at Johns Hopkins All Children's Hospital. She also is the hematology leader of the Young Women Bleeding Disorders/Menorrhagia Clinic, which focuses on a multidisciplinary approach to bleeding symptoms in girls and young women. Dr. Ayala also is involved in the Immune Dysregulation Clinic, which evaluates patients with autoimmune cytopenias in a multidisciplinary approach. Dr. Ayala joined the hospital in 2000. She was the chair of the Division of Hematology/Oncology between 2013-2017 and also served as interim director for the division between 2015-2016. Dr. Ayala's research experience includes multicenter national and international projects. Dr. Ayala received her medical degree from the University of Puerto Rico School of Medicine, her residency training at the San Juan City Hospital in Puerto Rico and her fellowship training at the Emory University School of Medicine Division of Pediatric Hematology/Oncology. Dr. Ayala is a member of the American Society of Pediatric Hematology/Oncology and the Hemophilia and Thrombosis Research Society.

Dr. Oshrine specializes in blood and marrow transplants as a pediatric hematologist/oncologist in the Johns Hopkins All Children’s Cancer & Blood Disorders Institute. His clinical focus is in the treatment of high-risk leukemias with blood and marrow transplantation, and his research focus is in immune recovery after transplant. He joined the hospital in 2014 after completing a fellowship in pediatric hematology/oncology at the Children’s Hospital of Philadelphia.He received the Excellence in Service & Professionalism Award in the 2018 Johns Hopkins Medicine Clinical Excellence Awards.