Charles Randy Bornmann, MD

Dr. Clifton Bingham is a Professor of Medicine, Director of the Johns Hopkins Arthritis Center, Director of the Center for Patient-Centered Outcomes Research in Rheumatology, Deputy Director for Research in the Division of Rheumatology, and Co-Director of the Rheumatic Diseases Research Core Center. He received his M.D. from Columbia University, where he also completed his Internal Medicine residency. He trained as a Fellow in both Rheumatology and in Allergy and Clinical Immunology at the Brigham and Women’s Hospital. Before coming to Hopkins in 2005, he was on faculty at NYU Hospital for Joint Diseases, where he founded a pioneering clinical and translational research center in rheumatology. He now directs the Johns Hopkins Arthritis Center, a group of 8 rheumatologists, 2 nurses, and a large clinical and research staff that sees more than 4500 patient visits each year, an integrates research with clinical care. His clinical interests are in the care of people living with Rheumatoid Arthritis (RA) and other forms of inflammatory arthritis. Dr. Bingham’s research experience has been diverse, and across the research continuum from bench to bedside. His early work focused on understanding the cytokine regulation of inflammatory mediator generation operative in rheumatologic and allergic diseases. He conducted prior translational research to better understand the role of initiating and amplifying pathways in RA, and has ongoing collaborations with several basic researchers to identify biomarkers for improved patient phenotyping and outcome prediction. Additional multidisciplinary clinical and translational work has focused on the role of periodontal disease and oral bacteria as triggers of RA. In the realm of clinical research, he has served as principal investigator and helped to design and analyze a number of NIH and industry-sponsored clinical trials of multiple agents in early to late phases of development for RA, psoriatic arthritis, and osteoarthritis. He has led several studies of the effects of biological and immunomodulatory therapies on responses to immunizations. A large amount of his current research is focused in the area of patient centered outcomes research, including patient reported outcome development, validation, and integration in clinical care. He serves as a member of the Executive Leadership Committee for the international Outcome Measures in Rheumatology (OMERACT) methodology group.He has authored more than 170 original research articles, reviews, and editorials, and 12 book chapters. He served as a Co-Editor for the journal of the American College of Rheumatology, Arthritis and Rheumatology, and as a reviewer for a number of rheumatology journals and national and international grant reviews.

Dr. Ana-Maria Orbai is an Associate Professor of Medicine in the Division of Rheumatology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include rheumatology and psoriatic arthritis. Dr. Orbai earned her M.D. from the Iuliu Hatieganu School of Medicine and Pharmacy, Cluj-Napoca, in Romania. She completed internship and residency training in internal medicine at the Johns Hopkins University-Sinai Hospital program. Subsequently, Dr. Orbai completed her post-doctoral fellowship training in rheumatology at Johns Hopkins. During her fellowship she earned her Master in Health Sciences degree in Clinical Investigation at the Johns Hopkins Bloomberg School of Public Health. Dr. Orbai directs the Psoriatic Arthritis Program in the Johns Hopkins Arthritis Center. Her clinical focus is psoriatic arthritis and spodyloarthritis. Dr. Orbai's research aims to understand psoriatic disease subtypes and improve treatment strategies for people with psoriatic arthritis. Dr. Orbai was awarded a Rheumatology Research Foundation Scientist Development award in 2014 and a Jerome L Greene Foundation Scholar award in 2018.

Johns Hopkins gastroenterologist David Muñiz Pedrogo is a physician-scientist who specializes in the treatment of inflammatory bowel disease (IBD). He sees patients who have ulcerative colitis and Crohn’s disease. A graduate of the University of Puerto Rico School of Medicine, Dr. Muñiz Pedrogo completed an internship and residency training in internal medicine at The Johns Hopkins Hospital, where he remained for fellowship training in gastroenterology and hepatology. He obtained advanced fellowship training in inflammatory bowel disease at the Mount Sinai Hospital in New York. Dr. Muñiz Pedrogo is the assistant director of the IBD clinical trials unit at Johns Hopkins. His research focuses on improving precision medicine for treatment of IBD by understanding the role of the immune system and gut microbiome in predicting response to various therapies and in predicting other clinical outcomes.