Howard M. Lederman, MD

Dr. Streiff's major clinical interest involves the prevention and treatment of venous thromboembolism. He has written several comprehensive reviews on vena caval filters and the management of venous thromboembolism in cancer patients. He chairs the Venous Thromboembolism Guideline Committee for the National Comprehensive Cancer Center Network and has served on international consensus panels to develop standardized guidelines for the use of vena caval filters in the management of venous thromboembolism. As a member of a Johns Hopkins Evidence-Based Practice Center panel, he participated in the development of evidence reports on the management of venous thromboembolism. His research on patients with malignant gliomas identified ABO blood group as a novel risk factor for VTE in this population. A multicenter clinical trial is now nearing completion to confirm these results and identify plasma markers of increased risk for venous thromboembolism in glioma patients. As Medical Director of the Anticoagulation Management Service and Outpatient Clinics, he and his colleagues from the Department of Pharmacy have been actively involved in developing policies and procedures for standardizing anticoagulation management and guidelines for VTE prevention at the Johns Hopkins Medical Institutions. As the consulting Hematologist for the Johns Hopkins Comprehensive Hemophilia Treatment Center, he is actively involved in the diagnosis and treatment of patients with hemophilia, von Willebrand disease and other hemostatic disorders.

Dr. David W. Cooke is an associate professor of pediatrics at the Johns Hopkins University School of Medicine. Dr. Cooke’s clinical activities include both a general pediatric endocrine clinic and a pediatric diabetes clinic.His clinical interests include all endocrine disorders in children and adolescents, including short stature, abnormal pubertal development, growth hormone dysregulation, thyroid disorders, hormone deficiencies, hypopituitarism, diabetes insipidis, pituitary adenoma, prolactinoma, goiter, Cushing's disease, Addison's disease, polycystic ovary syndrome, congenital adrenal hyperplasia and disorders of sexual differentiation, Turner syndrome and Klinefelter syndrome, among others.He serves as clinical director of the division of pediatric endocrinology and director of the Pediatric Endocrinology Fellowship Training Program at Johns Hopkins. He is a member of the Johns Hopkins Klinefelter Syndrome Center.Dr. Cooke completed his undergraduate studies at the Massachusetts Institute of Technology, and received his medical degree from the Duke University School of Medicine. He then completed his residency in pediatrics at The Johns Hopkins Hospital, where he also completed a fellowship in pediatric endocrinology.He has been a faculty member in the Division of Pediatric Endocrinology at the Johns Hopkins since 1993. After his fellowship, Dr. Cooke spent five years of additional research training in the Department of Biological Chemistry at Johns Hopkins, supported by an individual Physician Scientist Award from the National Institutes of Health (NIH).Dr. Cooke’s past research interest was the molecular basis of insulin resistance and obesity, with studies examining the role the adipocyte plays in these conditions. He had received research funding for these studies from the NIH and from the American Diabetes Association.Dr. Cooke is a recipient of the Johns Hopkins University School of Medicine Institute for Excellence in Education award for Outstanding Achievement in Medical and Biomedical Education. He also has been recognized as a Top Doctor by Baltimore magazine. Dr. Cooke is a member of the Society for Pediatric Research, the American Diabetes Association, the Endocrine Society and Pediatric Endocrinology Society. He is a fellow of the American Academy of Pediatrics.