Reference Diagnostics Inc

AVI BioPharma is a biopharmaceutical company that develops drugs to treat life-threatening diseases using its patented third generation antisense technology. It has completed clinical trials with its NeuGene antisense drugs in more than 300 subjects, addressing cardiovascular restenosis, infectious diseases, cancer, polycystic kidney disease and drug metabolism. Its most advanced cardiovascular program is for restenosis, where it has completed Phase II trials, evaluating its drug, Resten-NG. AVI BioPharma is also in a Phase II clinical trial with a drug for Hepatitis C infection and its influenza A drug candidate has been confirmed to have efficacy against avian influenza H5N1 in preclinical studies. AVI BioPharma maintains a location in Portland, Ore.

Metabolic Solutions provides a mass spectrometry analytical service to assist physicians, pharmaceutical developers and biomedical researchers in using isotope tracers to answer their questions about metabolism, nutrition and the presence of disease. The company is an independent, CLIA-certified clinical laboratory that provides kits and analysis for the Urea Breath Test to detect H. pylori infection, as well as the Hydrogen Breath Test for determining lactose intolerance. Metabolic Solutions laboratory is licensed to provide clinical lab services in all 50 states. All specimens are processed and results are reported within 24 hours of receipt. Metabolic Solutions also helps researchers to use stable and radioactive isotope tracers as biomarkers to study human and animal metabolic processes. The company s complete services include study protocol consultation, building custom test kits and a responsive analytical service compliant with current FDA Good Laboratory Practices. Since 1990, more than 500 researchers worldwide have relied on Metabolic Solutions for stable isotope measurements. The company is based in Nashua, N.H.

Millipore Research and Development is one of the leading providers of products and services to improve productivity in biopharmaceutical manufacturing and clinical, analytical and research laboratories. The company offers a range of products, such as blotting membranes, centrifugal filter units, environmental monitors, and filter holders and plates. Additionally, its product line includes filtration systems, fluid contamination kits, hazardous waste equipment, incubators and rapid microbiology systems. The company provides products for a variety of applications that include air and gas filtration, beverage processing, bioburden reduction, chromatography purification, disposable manufacturing and plasma fractionation. Millipore Research and Development employs more than 5,500 employees in over 47 offices worldwide. The company is located in Bedford, Mass., and is part of Millipore Corporation.