Choice Hotels

Holiday Inn Express Greenville NC is newly remodeled, ready for winter, and invites you to a warm, relaxing stay. As the air turns crisp, our hotel offers a cozy retreat with first-class amenities—making it one of Greenville’s finest destinations.Located in the heart of the Medical District, we are steps from ECU Medical Center, Leo Jenkins Cancer Center, East Carolina Heart Institute, Brody School of Medicine, and East Carolina Dental School. Whether for appointments, training, or visiting loved ones, our modern and updated spaces provide comfort and a welcoming atmosphere for all guests.Minutes from East Carolina University and its athletic venues—Dowdy-Ficklen Stadium, Clark-LeClair Stadium, and Minges Coliseum—perfect for winter sports or seasonal events. Elm Street Park and nearby cultural attractions offer plenty to enjoy. Business travelers value quick access to Thermo-Fisher Scientific, Catalent, Hyster-Yale, Grady-White Boats, Attindas, and Pitt Community College, ensuring productive visits.Enjoy thoughtful amenities: complimentary hot breakfast buffet, high-speed internet, meeting room, full Business Center, and IHG Rewards Club points for every visit, making each stay more rewarding.Just three miles from Pitt-Greenville Airport (PGV), with free airport shuttle, we make winter travel effortless. Cozy comforts and professional convenience ensure every detail is covered as you “Stay Smart” and enjoy your winter stay in Greenville NC.