Emmanuel Antonarakis, MD

Theodore DeWeese is The Frances Watt Baker, M.D., and Lenox D. Baker Jr., M.D. Dean of the Medical Faculty and CEO, Johns Hopkins Medicine. Dr. DeWeese is professor of oncology and urology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include prostate cancer, radiation oncology and urological oncology. He and his colleagues focus their research on developing new ways to enhance radiation-induced killing of prostate cancer cells. This includes development of novel, prostate cancer-targeted RNA molecules as well as new ways to modulate androgen receptor signaling. He and his colleagues also developed the first adenoviral gene therapy trial for prostate cancer, using a common cold virus to target cancer cells while leaving normal cells unharmed. Dr. DeWeese earned his M.D. from the University of Colorado Health Sciences Center. He completed his residency at The Johns Hopkins Hospital, serving as chief resident, and performed a laboratory research fellowship at the Johns Hopkins Oncology Center and the James Buchanan Brady Urological Institute. Dr. DeWeese's research interests include prostate cancer, DNA damage, and radiation sensitization. Dr. DeWeese has served on numerous committees and boards including as President and Chair of the Board for the American Society for Radiation Oncology. He also serves on committees for the American Association for Cancer Research and was appointed by the National Academy of Sciences as a scientific counselor for the Radiation Effects Research Foundation in Hiroshima, Japan. He has received numerous awards and honors, including several teaching awards from Johns Hopkins. Make A Gift

As an Assistant Professor in the Department of Radiation Oncology and Molecular Radiation Sciences, I specialize in palliative radiation oncology with a focus on improving access to high-quality, compassionate care for patients with advanced cancer. I am the founder and director of the Palliative Radiation and Supportive Medicine (PRISM) Service, a program dedicated to enhancing the role of radiation therapy in symptom management and end-of-life care. In addition, I am part of our breast radiation oncology team, and I guide clinical care and treatment strategies for patients with breast cancer at the Johns Hopkins Hospital. My clinical efforts center on expanding access to palliative radiation through infrastructural development, interdisciplinary collaboration, and innovative treatment approaches. I am deeply committed to advancing health equity and addressing disparities in cancer care delivery. My work also seeks to bridge the gap between radiation oncology and the health humanities, fostering a more holistic, human-centered approach to clinical practice that supports the emotional, social, and cultural dimensions of patient care.